Info

Mastering Nutrition

Hi, I'm Chris Masterjohn and I have a PhD in Nutritional Sciences. I am an entrepreneur in all things fitness, health, and nutrition. In this show I combine my scientific expertise with my out-of-the-box thinking to translate complex science into new, practical ideas that you can use to help yourself on your journey to vibrant health. This show will allow you to master the science of nutrition and apply it to your own life like a pro.
RSS Feed
Mastering Nutrition
2017
November
October
September
August
July
June
May
April
March
February
January


2016
December
November
October
August
July
June
May
April


Categories

All Episodes
Archives
Categories
Now displaying: August, 2017
Aug 31, 2017

This lesson looks at the third step of the citric acid cycle in much more detail, digging into the organic chemistry concepts involved in the conversion of isocitrate to α-ketoglutarate. We dive deep into this because it’s the only way to explain why this step parts ways with most other decarboxylation reactions in that it does not require thiamin (vitamin B1).

This, in turn, provides a basis for understanding why burning carbohydrate for fuel requires twice as much thiamin than burning fat, and why high-fat, low-carbohydrate, ketogenic diets can be used to overcome problems with thiamin deficiency or defects in thiamin-dependent enzymes. We conclude by looking at how this step allows the interconversion of amino acids and citric acid cycle intermediates, the role of vitamin B6 in this process, and the use of enzymes known as transaminases to diagnose B6 deficiency and liver dysfunction.

For the full episode, go to chrismasterjohnphd.com/mwm/2/6

Sign up for MWM Pro for early access to content, enhanced keyword searching, self-pacing tools, downloadable audio and transcripts, a rich array of hyperlinked further reading suggestions, and a community with a forum for each lesson.

Aug 30, 2017

Do you get dry skin when you put on muscle mass? It could be a zinc deficiency. Here's how to take care of it.

Aug 29, 2017

The fifth MWM Energy Metabolism lesson explores the third and fourth steps of the citric acid cycle and explains how the rate of ATP production is regulated according to the cell’s need for ATP. Together with lesson four, it explains how cells regulate their ATP production according to their needs and abilities. In the course of exploring this theme, we look at the role of AMP kinase (AMPK) in promoting energy uptake when ATP levels are low.

Watch the full lesson at chrismasterjohnphd.com/mwm/2/5

Sign up for MWM Pro for early access to content, enhanced keyword searching, self-pacing tools, downloadable audio and transcripts, a rich array of hyperlinked further reading suggestions, and a community with a forum for each lesson.

Aug 28, 2017

This lesson explores the first two steps of the citric acid cycle and explains how the rate of ATP production is regulated according to the abilities of the electron transport chain. Together with lesson five, it explains how cells regulate their ATP production according to their needs and abilities. In the course of exploring this theme, we examine the role of reactive oxygen species in diabetes.

Watch the full lesson at chrismasterjohnphd.com/mwm/2/4

Sign up for MWM Pro for early access to content, enhanced keyword searching, self-pacing tools, downloadable audio and transcripts, a rich array of hyperlinked further reading suggestions, and a community with a forum for each lesson.

Aug 27, 2017

This lesson provides an overview of the basic objectives of using the citric acid cycle and the electron transport chain to make ATP. We start here because, no matter whether we burn protein, carbs, or fat, these two interrelated systems are what is shared in common.

Watch the full lesson at chrismasterjohnphd.com/mwm/2/3

Sign up for MWM Pro for early access to content, enhanced keyword searching, self-pacing tools, downloadable audio and transcripts, a rich array of hyperlinked further reading suggestions, and a community with a forum for each lesson.

 
Aug 26, 2017

The second MWM energy metabolism looks at how we use enzymes to exert exquisite control over what happens inside our bodies.

If the second law of thermodynamics holds that entropy is always increasing, why don’t we reach maximum entropy right away? Why do we observe any order at all?  The activation energy represents the resistance to change that can be found in any substance. We exploit the concept biologically by maintaining a body temperature that provides insufficient energy for most relevant reactions to go forward without catalysis, and imposing upon this backdrop an expansive repertoire of enzymes that can, in a regulated fashion, lower the energy barriers sufficiently for reactions to go forward.

This lesson looks at how they do that, and how we regulate their activity.

Watch the full lesson at chrismasterjohnphd.com/mwm/2/2

Sign up for MWM Pro for early access to content, enhanced keyword searching, self-pacing tools, downloadable audio and transcripts, a rich array of hyperlinked further reading suggestions, and a community with a forum for each lesson.

Aug 25, 2017

The first MWM Energy Metabolism lesson answers the question, why do we have to eat such an enormous amount of food?

The answer is to comply with the second law of thermodynamics. If you have a chemistry background, you should recognize this as a light review of the thermodynamics unit from a general chemistry class, with its most essential concepts teased out and packed into a half hour lesson. If you don’t, you can use this as a basic foundation for understanding the biochemistry to follow.

The lesson relates the 2nd law to food coloring dispersing in water, how a hydropower plant operates, ATP production, and why we need to eat our bodyweight in food more than once a month. In the process, we have a little fun.

Watch the full lesson at chrismasterjohnphd.com/mwm/2/1.

Sign up for MWM Pro for early access to content, enhanced keyword searching, self-pacing tools, downloadable audio and transcripts, a rich array of hyperlinked further reading suggestions, and a community with a forum for each lesson.

Aug 25, 2017

Masterclass With Masterjohn Energy Metabolism is a structured course that begins with foundational principles and progresses to advanced topics to give you everything you need to know about the biochemistry of how we break down food for energy, use the energy, and store the excess.

It broadcasts FREE on YouTube and Facebook twice a week and is now in its 31st lesson.

As a subscriber to the Mastering Nutrition podcast, you will now get the cliff notes of these lessons in audio format. 

This gives you three ways to engage with the course:

  • If you just want the cliff notes, sit back and relax. As long as you're subscribed to the Mastering Nutrition podcast, they'll pop up in your feed one by one, every day that there's no other content released in the feed. That begins with lesson one later today.
  • If you want to watch the full lessons, you can do so using the YouTube playlist, by going to the videos section of my Facebook page and playing the playlist, or by going to chrismasterjohnphd.com, hovering over "Masterclass" in the main menu on desktop and clicking the dropdown arrow to the right of "Masterclass" on mobile, and choosing "The Free Version."
  • Sign up for MWM Pro for early access to content, enhanced keyword searching, self-pacing tools, downloadable audio and transcripts, a rich array of hyperlinked further reading suggestions, and a community with a forum for each lesson.

However you choose to engage, enjoy! 

Aug 12, 2017

MTHFR is an enzyme that allows folate (vitamin B9) to support the cellular process of methylation, which is important for the synthesis of creatine and phosphatidylcholine, the regulation of gene expression, neurotransmitter metabolism, and dozens of other processes. There are two common polymorphisms that decrease its activity, A1298C and C677T, with C677T having the stronger effect. Genetic decreases in MTHFR activity are associated with cardiovascular disease, neurologic and psychiatric disorders, pregnancy complications and birth defects, and cancer.

While discussions of these polymorphism tend to focus on repleting methyl-folate, this should only be a small piece of the puzzle. The bigger pieces of the puzzle are restoring choline, creatine, and glycine. 

In this episode, I describe how the methylation system works, how it's regulated, and how it's altered with MTHFR variations. I then use this to develop a detailed dietary strategy and an evaluative strategy to make sure the dietary strategy is working.

Show notes coming soon!

This episode is brought to you by Ample Meal. Ample is a meal-in-a-bottle that takes a total of two minutes to prepare, consume, and clean up. It provides a balance of fat, protein, and carbohydrate, plus all the vitamins and minerals you need in a single meal, all from a blend of natural ingredients. The protein is from whey and collagen. The fat is from coconut oil and macadamia nut oil. The carbohydrates, vitamins, and minerals come exclusively from food sources like sweet potatoes, bananas, cocoa powder, wheat and barley grass, and chlorella. I use Ample on Mondays when I have 12 hours of appointments with breaks no longer than 15 minutes. It keeps my brain going while I power through the long day, never letting food prep make me late for an appointment. Head to amplemeal.com and enter the promo code “MASTERJOHN” at checkout for a 15% discount off your first order.

This episode is brought to you by US Wellness Meats. I use their liverwurst as a convenient way to make a sustainable habit of eating a diversity of organ meats. They also have a milder braunschweiger and an even milder head cheese that gives you similar benefits, as well as a wide array of other meat products, all from animals raised on pasture. Head to grasslandbeef.com and enter promo code “Chris” at checkout to get a 15% discount on any order that is at least 7 pounds and is at least $75 after applying the discount but under 40 pounds (it can be 39.99 lbs, but not 40). You can use this discount code not once, but twice!

1