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Mastering Nutrition

Hi, I'm Chris Masterjohn and I have a PhD in Nutritional Sciences. I am an entrepreneur in all things fitness, health, and nutrition. In this show I combine my scientific expertise with my out-of-the-box thinking to translate complex science into new, practical ideas that you can use to help yourself on your journey to vibrant health. This show will allow you to master the science of nutrition and apply it to your own life like a pro.
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Now displaying: Page 4
Nov 27, 2020

Question:  What’s the best nutrition for panic and anxiety?

Methylation is overwhelmingly important. I do think that other factors impacting dopamine can be relevant in the sense that the main way that methylation regulates mental rigidity is through decreasing the pool of tonic dopamine, which favors mental flexibility. And so, you can also favor mental flexibility by increasing the activity of dopamine receptors that mediate the basic response dopamine. 

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 26, 2020

Question:  What determines the absorption of nutrients?

This is a gigantic question because what determines the absorption of any given nutrient is independent for that nutrient. And so, it’s different for every nutrient. And we just don't have that level of data to drive modeling of absorption of other nutrients in an accurate way.

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 25, 2020

Question:  Do low serine levels require IV supplements?

You're probably just depleting serine through the CBS pathway and just eat more protein and consider supplementing glycine or collagen along with it. I don't see why that would require IV supplements. 

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 24, 2020

Question: How to fix high iron and calcium, low copper and magnesium, without blood donation?

Your only options for decreasing iron levels are to eat a low meat vegetarian diet high in vegetables, nuts, seeds, and whole grains. That's probably your best bet.

But the thing is, a very vegetable rich diet is gonna be pretty high in copper. And it's going to be high in iron too, but it's gonna be very poorly absorbable iron. And you know, especially if you eat a lot of whole grains, nuts, seeds, and legumes, you can get a lot of phytate. When doing that, you should probably supplement with zinc. You could consider supplementing with copper. The preferred copper for me would be liver or liver capsules, which I think provide copper way out sized to the iron that they provide. I think that's your best option when you don't have giving blood as an option to get rid of iron. If needed, you can do supplemental phytate, but I would use that as a last resort rather than a first one. 

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 23, 2020

Question: How much time should separate my zinc supplements and nut consumption?

So, phytate primarily inhibits absorption of zinc and iron. I think you're gonna have a much lower probability of zinc encountering phytate if you take the zinc 2 hours after eating the phytate than if you take the zinc while you eat the phytate. But you know, if you're trying to be maximally conscientious, 3 hours after the meal.

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 20, 2020

Question: What’s the safe use of an iodine nasal spray?

So, the iodine in the food and supplement guide for the coronavirus most recent version, I included iodine as a nasal spray. It's very important to look at the percentages. And so, 0.5% is the concentration recommended and that means that if you get a 10% solution, which is the most common one, you want to dilute it down 20-fold, which means taking one part of the 10% solution 19 parts water. If you have a different percentage starting solution, you wanna dilute it differently. And it's critically important that you dilute it properly. And so, you should have someone double check your work if you're doing your own math or triple check your work because higher concentrations can cause damage to the nasal tissue. But in terms of how often what I recommend doing is using it as a before and after in potential exposures.

For additional important safety information please see here:

https://chrismasterjohnphd.com/covid-19/povidone-iodine-safety-efficacy-and-lugols

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 19, 2020

Question: Why would ferritin be extremely high when transferrin saturation is low?

Ferritin as a potential indicator of iron overload should not be anywhere near the level that was set to try to rule in biopsy provable hemochromatosis that is just a profoundly negligent approach to setting the range for ferritin. Now, I think part of what has stopped, you know— This mostly is a problem of the binary diagnostic mindset of conventional medicine. So, I'm not saying that this mindset is not useful. It is tremendously useful, but too many people confuse it for a reality when in fact it is a reality distortion filter meant to more efficiently triage people through various treatments or nontreatments.

It may be inflammation as you very well tried to feather out. And if it's not that, it's probably oxidative stress. So, I’m not gonna say that’s the only other thing it could be. And for the record, you cannot rule out hemochromatosis genetics with 23andMe or any other genetic test by anyone because there are a small percentage of hemochromatosis genetics that are not in the HFE genes and no one has a panel for them. And so, it’s improbable that it’s hemochromatosis based on 23andMe. You can’t rule it out, but I would say it’s probably not hemochromatosis because his iron is low. And so, you know, I'm highly suspicious of oxidative stress, which also upregulates ferritin. If you have Testing Nutritional Status: The Ultimate Cheat Sheet, I would measure everything in the oxidative stress section.

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 18, 2020

Question: Can carnitine be used for fatty liver instead of choline?

The role of choline and the role of carnitine have nothing to do with one another. Choline is going to help move fat out of the liver. Carnitine is going to help fat get into the mitochondria to be burned for energy. So, first of all, I think one thing that’s important to note is that you're gonna get more bang for the buck by fixing the things that are wrong rather than pulling on levers that are working perfectly fine. 

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 


DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 17, 2020

Question: Is it OK to drink a pint of Gerolsteiner mineral water a day?

It’s significantly less than a bottle. I guess conceivably if you're also drinking a lot of milk, or eating a lot of cheese, or supplementing with calcium, or taking bone meal powder, I guess you can get too much calcium. I wouldn’t really worry about it from 1 pint. I do think that the main concern with carbonated beverages of any type is that you have too much acid running over your teeth a lot. So, I think it's wise to drink this in a way that tends to bypass your teeth. You can do it more effectively if you use a straw, but I think you can manipulate the bottle in your mouth to kind of pour it beyond your teeth, which I think is a good thing to do. Probably the best thing that you can do for that is before you brush your teeth, make sure that you swish with water or baking soda. 


If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at
https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 16, 2020

Question: Cataracts: what are the roles of methylglyoxal and polyols?

Is the polyol pathway activation and methylglyoxal independent causes of cataract formation or are they related to one another? And the answer is a little bit of both. You know, if independent means unrelated, then they’re related. Not independent. But they are independent in the sense that you could have more of one. You know, you could do something that increases one and not the other or at least disproportionately increases one versus the other. So, the polyol pathway, I think the best way to describe that is under conditions of severe hyperglycemia where you have too much sugar to be disposed of in the normal routes. You can use the sugar to synthesize polyols.

Glutathione is needed, among other things, to detoxify methylglyoxal. And methylglyoxal causes cataracts. Now, that's not to say that there aren’t other things going on. I mean, certainly glutathione is also needed to defend against oxidative stress. But then again, this might not be the only way that oxidative stress contributes to cataracts, but oxidative stress increases methylglyoxal generation in part by decreasing the activity of glyceraldehyde 3-phosphate dehydrogenase or GAPDH, which is the enzyme within glycolysis that is responsible for clearing what are known as triose phosphates.

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at
https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. 

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 13, 2020

Question: Is the sugar in Life Extension Enhanced Zinc Acetate lozenges a problem?

In that kind of protocol attuned to the progress of the potential cold, I find no alternative is more effective than the zinc acetate lozenges. And so, therefore, I'm willing to consume 40 or 60 grams of sugar for like 1 day or 2 days and then have it taper off granted— I might have a totally different attitude if I had diabetes. But from a cost-benefit analysis, I don't think consuming 40 grams of sugar once for a healthy person is going to cause any permanent damage. It's not the ideal thing, but the problem is that all the alternative zinc lozenges have generally involved factors that decrease the zinc ionization in the mouth.

References:

https://chrismasterjohnphd.com/podcast/2016/12/26/zinc-definitely-fights-colds-youre-probably-using-wrong-kind

https://chrismasterjohnphd.com/covid-19/treatment-of-covid-19-with-high-dose-zinc-4-cases 


If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at
https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life. 

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 


DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 12, 2020

Question: If I use SAMe for depression, what do I need for nutritional balance?

Nutrition wise, I think the most important thing would be to make sure that you have an adequate glycine status. And you know, I don't know what your background is in terms of other issues, but the glycine buffer system, which is how you buffer excess methyl groups, which is what you would have if you take a large bolus of SAMe.

Other nutritional concern would be having enough molybdenum. Generally, you're gonna have enough with 100 mcg a day. If you're eating liver once a week, you probably have enough, but there's no harm in taking like 500 mcg a day, so not really a problem if you want to supplement there just to make sure it's not an issue. 

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 


DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 11, 2020

Question: Should I take iron every day or use alternate day dosing?

Reference: https://haematologica.org/article/view/9379

So, according to this abstract, in iron depleted women without anemia, oral iron supplements induce an increase in serum hepcidin that persist for 24 hours, decreasing iron absorption from supplements given later on the same or next day. Consequently, iron absorption from supplements is highest if iron is given on alternate days.

Bringing this back to a practical level, is it easier for you to maintain a habit of every day dosing or is it easier for you to maintain a habit of every other day dosing? Because I know for myself by far and away, the easiest thing for me to do is to have a little turntable inside my cabinet of everything I’m gonna take in the morning just take it all. The more complicated things get, the more you need a list or you need an app that reminds you to take it every other day.

When I wake up in the morning half the time I am not going to remember whether I took it the day before or not. So, I'm gonna have to keep track of that somehow. It's just so much more practical to take something every day at the same time than it is to try to impose more complicated dosing on it that I would want to be much more convinced that there is a real effect before I was going to bother with that greater difficulty of sustaining the habit. 

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.


For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 10, 2020

I'm not sure what the best dosing is given that it hasn't actually been studied fully, but I believe that it was estimated that in the people who have the highest collagen waste during collagen turnover that they can run short of glycine about 60 grams a day whereas I believe the more conservative estimate of glycine requirements based on people that turnover collagen much more efficiently.

I would say that as a general rule, you should assume that you want something spread out as much as possible rather than the reverse if you don't have the data showing that it’s okay or better to have it all at once because wherever there is data or wherever there is a plausible rationale, it's almost always the case that it's better to have it spread out.

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 


DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Nov 9, 2020

Question: Where should I buy my chicken products?

You may have local options. And a good place to look for local options would be eatwild.com. I’m assuming it’s still up. That was a great database and probably still is a great database of pasture-raised products of any type. Not just chicken. And then of course, there are the mail order companies that I have exclusive discounts with inside the Masterpass program, most of which sell chicken products.

So, White Oak Pastures, North Star Bison who focuses on bison but I believe they have chicken also. And U.S. Wellness whereas  chicken might not be their main thing, I’m pretty sure they have chicken. Generally those companies, even if they don’t advertise themselves as mainly being about chicken, they usually will have some chicken.


If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at
https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

For the remainder of 2020, I will be working full-time on finishing my Vitamins and Minerals 101 book, while reserving a portion of my time for consulting clients. You can pre-order my book at https://chrismasterjohnphd.com/book. You can sign up for a consultation at https://chrismasterjohnphd.com/consultations 

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Sep 17, 2020

I don't usually interview people on my podcast, but this is an important exception and I'd appreciate it if you'd share it far and wide.

Here's the YouTube version:

COVID Conversations: Gabriela Gomes on Herd Immunity

Gabriela Gomes is Professor of Mathematics and Statistics at University of Strathclyde Glasgow and corresponding author of the recent paper, "Herd immunity thresholds for SARS-CoV-2 estimated from unfolding epidemics," one of the papers arguing that the herd immunity threshold is on the order of 10-20% in the European communities they studied rather than the 60-80% more commonly cited, and she's here to talk about herd immunity and COVID-19.

Here's a list of topics we covered:

00:00:01 Introduction

00:01:28 Gabriela's body of research showing the importance of individual variation in susceptibility to infectious diseases.

00:04:25 Conventional models that don't take into account individual variation overestimate the size of epidemics and overestimate the effect of interventions.

00:05:21 How has her research been received by her colleagues?

00:09:30 The evolution of immunity has to be through the action of natural selection on variation, making it logically necessary that variation exists.

00:11:54 Nutrition scientists underestimated variation in nutritional requirements but have been much more receptive than infectious disease epidemiologists to incorporating it into their models.

00:15:51 The ability to identify a single necessary factor in infectious disease spread has biased the field toward a ground-up mechanistic model to vet the inclusion of variables.

00:22:34 What is herd immunity?

00:26:11 Tuberculosis disappeared because socioeconomic conditions improved.

00:29:06 Until the vaccine, measles cycled in and out of herd immunity as new infants entered the susceptible population.

00:31:13 Measles is much more transmissible than SARS-CoV-2.

00:32:21 SARS was contained before it had a chance to spread.

00:34:08 Herd immunity is not the end of concern about a disease.

00:34:33 The herd immunity threshold for COVID will be crossed many times, but crossing it the first time is the end of the "pandemic phase."

00:39:16 The seasonality of the flu is influenced not only by weather and social patterns that influence transmissibility, but also by cyclically crossing in and out of herd immunity. Viral mutations can be the trigger to temporarily cycle out of herd immunity.

00:46:57 Why conventional herd immunity threshold calculations say the threshold is 60-80% for COVID, but why Gabriela's model says 10-20%.

00:51:45 How do we know what the degree of variation is?

00:54:56 Gabriela's conclusions are similar to those reached by other researchers when looking at NYC and Chicago.

00:56:48 As long as susceptibility is correlated to infectiousness, natural infections will remove the most infectious people early on.

01:01:26 Is it possible that lockdowns and social distancing are solely responsible for everything we attribute to herd immunity?

01:08:30 How likely is it that fading immunity and reinfection would render the herd immunity model useless?

01:11:19 What does the New York City data tell us about herd immunity and reinfection?

01:15:32 What does Spain's second wave tell us?

01:19:21 We discuss Harvard Professor Miguel Hernán's suggestion on Twitter that NYC is doing so much better than Madrid because NYC had superior testing, contact tracing, and phased reopening.

01:23:16 Misunderstanding herd immunity has huge economic consequences.

01:25:13 Should we be looking at cases, hospitalizations, deaths, or seroprevalence as our primary metric?

01:35:28 We discuss University of Minnesota epidemiologist Michael Osterholm's suggestion that scientists modeling a 20% herd immunity threshold are "not connected with real-world thinking" and that the much higher infection rates in prisons and a South Korean call center show that the herd immunity threshold cannot be anywhere near as low as 20%.

01:41:05 Gabriela is hoping to find more collaborators to extend the modeling to more communities.

01:41:55 Why approaching herd immunity rapidly allows you to massively overshoot the threshold

01:46:10 How has her research been received by peer review, the press, and her colleagues?

01:49:00 What developments will she be looking for that would falsify her model?

01:50:39 What are the policy implications of her research?

Here's how you can share this on social media:

Stay safe and healthy,
Chris

Aug 31, 2020

Read the written version here, with links to the original references:

https://chrismasterjohnphd.com/covid-19/are-we-already-reaching-herd-immunity

Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates 

Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss 

Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass.

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DISCUSS!

Here are three ways to discuss this topic, including asking me questions and getting a response:

The Masterpass FREE Forum. This forum is free and open to anyone to participate. Anything related to health and nutrition, including all aspects of the coronavirus, is welcome. I will do my best to participate several times a week, though I expect this to eventually be very large and may at some point have to participate on a weekly basis if it starts to take on a life of its own. Join for free at chrismasterjohnphd.com/discuss

The Coronavirus Forum. This is for anyone who purchases The Food and Supplement Guide for the Coronavirus, pre-orders my upcoming Vitamins and Minerals 101 book, or joins the CMJ Masterpass (if you join, use the coupon code COVID19 for 10% off the membership price). This forum is dedicated specifically to the coronavirus, has subsections based on topics (nutrition, medicine, lifestyle, mechanisms of disease), and has a section where the archive version of this newsletter is directly linked and each newsletter can be discussed as an individual thread. I consistently participate in this forum 3-5 times a week. Purchase the guide at chrismasterjohnphd.com/coronavirus

The Masterpass Discussion Group. Preserved for those who join the CMJ Masterpass, it's the best place to ask me questions in a fairly intimate environment and get a rapid response. All topics I cover are fair game, and I consistently participate approximately five times per week. The Masterpass also has monthly live Zoom Q&As that are even more intimate. Join the Masterpass at chrismasterjohnphd.com/masterpass

SUPPORT

These research updates are made possible by purchases of The Food and Supplement Guide to the Coronavirus. The guide contains my most up-to-date conclusions about what we should be doing for nutritional and herbal support on top of hygiene and social distancing for added protection. Due to the absence of randomized controlled trials testing nutritional or herbal prevention, these are my best guesses for what is likely to work without significant risk of harm, based on the existing science. By purchasing the guide, you are enabling me to continue devoting my skills to the most important issue we now face. I am genuinely grateful for your contribution. You can purchase a copy at chrismasterjohnphd.com/coronavirus

You can get the guide for free if you pre-order my upcoming book, Vitamins and Minerals 101: How to Get the Nutrients You Need on Any Diet (to be released when the COVID-19 crisis subsides). You can pre-order it at chrismasterjohnphd.com/book

You can also get the guide free when you join the CMJ Masterpass, which is meant to help people with significant health and wellness expenditures consistently save money by returning marketing cost of the companies involved back to the members as rebates. A membership also saves you 30% on pre-orders of the paperback and 50% on pre-orders of the digital versions of my book. You can sign up at chrismasterjohnphd.com/masterpass

SUBSCRIBE

This series is based on my free daily newsletter, COVID-19 Research Updates. As a result of the time it takes to produce an video or podcast from a newsletter I wrote up, there's a slight delay between when I publish the newsletter and when you watch or listen to this. When you subscribe to the newsletter, you get the latest of my research every single day as soon as it's ready to come out. You get references and links to the sources for all the information, and you immediately get an archive of all the past issues. You can sign up at chrismasterjohnphd.com/covid19-updates

DISCLAIMER

I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have a PhD in Nutritional Sciences and my expertise is in conducting and interpreting research related to my field. Please consult your physician before doing anything for prevention or treatment of COVID-19, and please seek the help of a physician immediately if you believe you may have COVID-19.

STAY SAFE AND HEALTHY!

Aug 27, 2020

Question: Why would blood glucose go up on a low-carb diet?

When you're adapted to low insulin levels with lower GLUT expression, but you want to get glucose into muscle, you're going to need higher blood glucose levels to do it.
I think elevated blood glucose is sufficiently known to be pathological that it would be unwise to assume the sort of more generous interpretation of that as a physiological response. I think it would be a much better approach to do what you need to do to get your blood glucose levels into the healthy range. Otherwise, I think it's quite a gamble to presume innocence of that elevated blood glucose.

This Q&A can also be found as part of a much longer episode, here.

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

There are two ways to discuss this episode:
Discuss it in The Masterpass FREE Forum, which is freely open to everyone, at https://chrismasterjohnphd.com/discuss
If you’re a Masterpass member, discuss it in the Masterpass Discussion Group, found in your dashboard.

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Aug 26, 2020

Question: Why do thyroid levels drop on a low-carb diet?

So insulin and leptin are both positive regulators of thyroid hormone, production, and conversion. And generally I do think there's probably a larger effect from thyroid production than peripheral conversion. I'm not too sure about that, but insulin does directly regulate thyroid. It has TSH-like effects on the thyroid gland. It doesn't replicate all of TSH's effects, but it does replicate a portion of them. So basically, more or less, have like TSH amplification with insulin.

This Q&A can also be found as part of a much longer episode, here.

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

There are two ways to discuss this episode:

  • Discuss it in The Masterpass FREE Forum, which is freely open to everyone, at https://chrismasterjohnphd.com/discuss 
  • If you’re a Masterpass member, discuss it in the Masterpass Discussion Group, found in your dashboard.

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Aug 25, 2020

Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates 

Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss 

Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass.

Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismasterjohnphd.com/coronavirus 

Get the guide for free when pre-ordering my Vitamins and Minerals 101 book: https://chrismasterjohnphd.com/book 

Get the guide for free and get 30-50% off the pre-orders of my book when you sign up for the CMJ Masterpass: https://chrismasterjohnphd.com/masterpass 

DISCUSS!

Here are three ways to discuss this topic, including asking me questions and getting a response:

The Masterpass FREE Forum. This forum is free and open to anyone to participate. Anything related to health and nutrition, including all aspects of the coronavirus, is welcome. I will do my best to participate several times a week, though I expect this to eventually be very large and may at some point have to participate on a weekly basis if it starts to take on a life of its own. Join for free at chrismasterjohnphd.com/discuss

The Coronavirus Forum. This is for anyone who purchases The Food and Supplement Guide for the Coronavirus, pre-orders my upcoming Vitamins and Minerals 101 book, or joins the CMJ Masterpass (if you join, use the coupon code COVID19 for 10% off the membership price). This forum is dedicated specifically to the coronavirus, has subsections based on topics (nutrition, medicine, lifestyle, mechanisms of disease), and has a section where the archive version of this newsletter is directly linked and each newsletter can be discussed as an individual thread. I consistently participate in this forum 3-5 times a week. Purchase the guide at chrismasterjohnphd.com/coronavirus

The Masterpass Discussion Group. Preserved for those who join the CMJ Masterpass, it's the best place to ask me questions in a fairly intimate environment and get a rapid response. All topics I cover are fair game, and I consistently participate approximately five times per week. The Masterpass also has monthly live Zoom Q&As that are even more intimate. Join the Masterpass at chrismasterjohnphd.com/masterpass

SUPPORT

These research updates are made possible by purchases of The Food and Supplement Guide to the Coronavirus. The guide contains my most up-to-date conclusions about what we should be doing for nutritional and herbal support on top of hygiene and social distancing for added protection. Due to the absence of randomized controlled trials testing nutritional or herbal prevention, these are my best guesses for what is likely to work without significant risk of harm, based on the existing science. By purchasing the guide, you are enabling me to continue devoting my skills to the most important issue we now face. I am genuinely grateful for your contribution. You can purchase a copy at chrismasterjohnphd.com/coronavirus

You can get the guide for free if you pre-order my upcoming book, Vitamins and Minerals 101: How to Get the Nutrients You Need on Any Diet (to be released when the COVID-19 crisis subsides). You can pre-order it at chrismasterjohnphd.com/book

You can also get the guide free when you join the CMJ Masterpass, which is meant to help people with significant health and wellness expenditures consistently save money by returning marketing cost of the companies involved back to the members as rebates. A membership also saves you 30% on pre-orders of the paperback and 50% on pre-orders of the digital versions of my book. You can sign up at chrismasterjohnphd.com/masterpass

SUBSCRIBE

This series is based on my free daily newsletter, COVID-19 Research Updates. As a result of the time it takes to produce an video or podcast from a newsletter I wrote up, there's a slight delay between when I publish the newsletter and when you watch or listen to this. When you subscribe to the newsletter, you get the latest of my research every single day as soon as it's ready to come out. You get references and links to the sources for all the information, and you immediately get an archive of all the past issues. You can sign up at chrismasterjohnphd.com/covid19-updates

DISCLAIMER

I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have a PhD in Nutritional Sciences and my expertise is in conducting and interpreting research related to my field. Please consult your physician before doing anything for prevention or treatment of COVID-19, and please seek the help of a physician immediately if you believe you may have COVID-19.

STAY SAFE AND HEALTHY!

Aug 25, 2020

Question: Is hydrogen sulfide produced in the gut a bad thing, and what to do about it?

I agree that most people that have this problem have some kind of deranged sulfur metabolism, but I don't see why that makes it a physiological adaptation rather than a pathological condition. The correlation is probably a direct result of the predominance of sulfur-metabolizing bacteria in the gut, which is a bad thing that is actually causing the derangement of sulfur metabolism.

Well, you could go the antibiotic route. And I think metronidozole, and let me see if I can dig this up quickly because I have done a lot of research on this issue for one of my clients. Okay. So from the research I was looking at, metronidozole is very effective against sulfur-metabolizing bacteria. But isn't that reliably delivered to the stool and maybe could be used as an enema. But I think generally, it is used. And then I think there's one other one that's sometimes used. I forgot what the other one is. I think it's... Okay. I can't find it. Anyway, you can go the antibiotic route under the guidance of a prescribing specialist.

This Q&A can also be found as part of a much longer episode, here.

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

There are two ways to discuss this episode:

  • Discuss it in The Masterpass FREE Forum, which is freely open to everyone, at https://chrismasterjohnphd.com/discuss 
  • If you’re a Masterpass member, discuss it in the Masterpass Discussion Group, found in your dashboard.

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Aug 24, 2020

Question: What if low-carb makes me wake up to pee? 

I would start by looking at your blood sugar. So I do think it's possible that if your blood sugar. Second of all, it's stimulated by salt. So salt at night might help. Third of all, in order to make it you need copper, vitamin C, and zinc. And then, fourth of all, you need, going past that, I also suggest trying to get deeper sleep. You might want to look at the quality of your sleep. So, I do think generally carbs help people get better sleep, but I do think that a ketogenic diet elevates GABA. And so I think there's a subset of people who would get better and deeper sleep on keto because of the increased brain GABA.

This Q&A can also be found as part of a much longer episode, here. 

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

There are two ways to discuss this episode:

  • Discuss it in The Masterpass FREE Forum, which is freely open to everyone, at https://chrismasterjohnphd.com/discuss 
  • If you’re a Masterpass member, discuss it in the Masterpass Discussion Group, found in your dashboard.

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Aug 24, 2020

Watch the YouTube video to see the slides:
https://youtu.be/Az0f6VPaEAA

Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates 

Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss 

Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass.

Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismasterjohnphd.com/coronavirus 

Get the guide for free when pre-ordering my Vitamins and Minerals 101 book: https://chrismasterjohnphd.com/book 

Get the guide for free and get 30-50% off the pre-orders of my book when you sign up for the CMJ Masterpass: https://chrismasterjohnphd.com/masterpass 

DISCUSS!

Here are three ways to discuss this topic, including asking me questions and getting a response:

The Masterpass FREE Forum. This forum is free and open to anyone to participate. Anything related to health and nutrition, including all aspects of the coronavirus, is welcome. I will do my best to participate several times a week, though I expect this to eventually be very large and may at some point have to participate on a weekly basis if it starts to take on a life of its own. Join for free at chrismasterjohnphd.com/discuss

The Coronavirus Forum. This is for anyone who purchases The Food and Supplement Guide for the Coronavirus, pre-orders my upcoming Vitamins and Minerals 101 book, or joins the CMJ Masterpass (if you join, use the coupon code COVID19 for 10% off the membership price). This forum is dedicated specifically to the coronavirus, has subsections based on topics (nutrition, medicine, lifestyle, mechanisms of disease), and has a section where the archive version of this newsletter is directly linked and each newsletter can be discussed as an individual thread. I consistently participate in this forum 3-5 times a week. Purchase the guide at chrismasterjohnphd.com/coronavirus

The Masterpass Discussion Group. Preserved for those who join the CMJ Masterpass, it's the best place to ask me questions in a fairly intimate environment and get a rapid response. All topics I cover are fair game, and I consistently participate approximately five times per week. The Masterpass also has monthly live Zoom Q&As that are even more intimate. Join the Masterpass at chrismasterjohnphd.com/masterpass

SUPPORT

These research updates are made possible by purchases of The Food and Supplement Guide to the Coronavirus. The guide contains my most up-to-date conclusions about what we should be doing for nutritional and herbal support on top of hygiene and social distancing for added protection. Due to the absence of randomized controlled trials testing nutritional or herbal prevention, these are my best guesses for what is likely to work without significant risk of harm, based on the existing science. By purchasing the guide, you are enabling me to continue devoting my skills to the most important issue we now face. I am genuinely grateful for your contribution. You can purchase a copy at chrismasterjohnphd.com/coronavirus

You can get the guide for free if you pre-order my upcoming book, Vitamins and Minerals 101: How to Get the Nutrients You Need on Any Diet (to be released when the COVID-19 crisis subsides). You can pre-order it at chrismasterjohnphd.com/book

You can also get the guide free when you join the CMJ Masterpass, which is meant to help people with significant health and wellness expenditures consistently save money by returning marketing cost of the companies involved back to the members as rebates. A membership also saves you 30% on pre-orders of the paperback and 50% on pre-orders of the digital versions of my book. You can sign up at chrismasterjohnphd.com/masterpass

SUBSCRIBE

This series is based on my free daily newsletter, COVID-19 Research Updates. As a result of the time it takes to produce an video or podcast from a newsletter I wrote up, there's a slight delay between when I publish the newsletter and when you watch or listen to this. When you subscribe to the newsletter, you get the latest of my research every single day as soon as it's ready to come out. You get references and links to the sources for all the information, and you immediately get an archive of all the past issues. You can sign up at chrismasterjohnphd.com/covid19-updates

DISCLAIMER

I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have a PhD in Nutritional Sciences and my expertise is in conducting and interpreting research related to my field. Please consult your physician before doing anything for prevention or treatment of COVID-19, and please seek the help of a physician immediately if you believe you may have COVID-19.

STAY SAFE AND HEALTHY!

Aug 21, 2020

Question: How does someone get arachidonic acid and choline without eggs and liver?

So apart from liver and egg yolks, I think that it is very difficult to get enough arachidonic acid from food. Yes, GLA might help, but there's actually arachiodonic acid supplements. And for the vegans out there, I don't know if the production process is strictly vegan, but they are derived from a specific mushroom and you can get them on Amazon. So I think supplementing with arachidonic acid is probably the most direct way to do that. And then evening primrose or a barrage oil could help provide precursors to arachidonic acid.

This Q&A can also be found as part of a much longer episode, here. 

If you would like to be part of the next live Ask Me Anything About Nutrition, sign up for the CMJ Masterpass, which includes access to these live Zoom sessions, a private discussion group, premium features on all my content, and hundreds of dollars of exclusive discounts. You can sign up at https://chrismasterjohnphd.com/masterpass/ and use the code QANDA to get 10% off the membership for life.

There are two ways to discuss this episode:

  • Discuss it in The Masterpass FREE Forum, which is freely open to everyone, at https://chrismasterjohnphd.com/discuss 
  • If you’re a Masterpass member, discuss it in the Masterpass Discussion Group, found in your dashboard.

DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.

Aug 21, 2020

Sign up for the free newsletter: https://chrismasterjohnphd.com/covid19-updates 

Discuss this in the Masterpass Free Forum at https://chrismasterjohnphd.com/discuss 

Discuss this in the Coronavirus Forum when you purchase the guide, pre-order my upcoming book, or join the CMJ Masterpass.

Support the service by purchasing a copy of The Food and Supplement Guide for the Coronavirus: https://chrismasterjohnphd.com/coronavirus 

Get the guide for free when pre-ordering my Vitamins and Minerals 101 book: https://chrismasterjohnphd.com/book 

Get the guide for free and get 30-50% off the pre-orders of my book when you sign up for the CMJ Masterpass: https://chrismasterjohnphd.com/masterpass 

DISCUSS!

Here are three ways to discuss this topic, including asking me questions and getting a response:

The Masterpass FREE Forum. This forum is free and open to anyone to participate. Anything related to health and nutrition, including all aspects of the coronavirus, is welcome. I will do my best to participate several times a week, though I expect this to eventually be very large and may at some point have to participate on a weekly basis if it starts to take on a life of its own. Join for free at chrismasterjohnphd.com/discuss

The Coronavirus Forum. This is for anyone who purchases The Food and Supplement Guide for the Coronavirus, pre-orders my upcoming Vitamins and Minerals 101 book, or joins the CMJ Masterpass (if you join, use the coupon code COVID19 for 10% off the membership price). This forum is dedicated specifically to the coronavirus, has subsections based on topics (nutrition, medicine, lifestyle, mechanisms of disease), and has a section where the archive version of this newsletter is directly linked and each newsletter can be discussed as an individual thread. I consistently participate in this forum 3-5 times a week. Purchase the guide at chrismasterjohnphd.com/coronavirus

The Masterpass Discussion Group. Preserved for those who join the CMJ Masterpass, it's the best place to ask me questions in a fairly intimate environment and get a rapid response. All topics I cover are fair game, and I consistently participate approximately five times per week. The Masterpass also has monthly live Zoom Q&As that are even more intimate. Join the Masterpass at chrismasterjohnphd.com/masterpass

SUPPORT

These research updates are made possible by purchases of The Food and Supplement Guide to the Coronavirus. The guide contains my most up-to-date conclusions about what we should be doing for nutritional and herbal support on top of hygiene and social distancing for added protection. Due to the absence of randomized controlled trials testing nutritional or herbal prevention, these are my best guesses for what is likely to work without significant risk of harm, based on the existing science. By purchasing the guide, you are enabling me to continue devoting my skills to the most important issue we now face. I am genuinely grateful for your contribution. You can purchase a copy at chrismasterjohnphd.com/coronavirus

You can get the guide for free if you pre-order my upcoming book, Vitamins and Minerals 101: How to Get the Nutrients You Need on Any Diet (to be released when the COVID-19 crisis subsides). You can pre-order it at chrismasterjohnphd.com/book

You can also get the guide free when you join the CMJ Masterpass, which is meant to help people with significant health and wellness expenditures consistently save money by returning marketing cost of the companies involved back to the members as rebates. A membership also saves you 30% on pre-orders of the paperback and 50% on pre-orders of the digital versions of my book. You can sign up at chrismasterjohnphd.com/masterpass

SUBSCRIBE

This series is based on my free daily newsletter, COVID-19 Research Updates. As a result of the time it takes to produce an video or podcast from a newsletter I wrote up, there's a slight delay between when I publish the newsletter and when you watch or listen to this. When you subscribe to the newsletter, you get the latest of my research every single day as soon as it's ready to come out. You get references and links to the sources for all the information, and you immediately get an archive of all the past issues. You can sign up at chrismasterjohnphd.com/covid19-updates

DISCLAIMER

I am not a medical doctor and this is not medical advice. I am also not an infectious disease epidemiologist and I am not speaking on behalf of infectious disease epidemiologists. I have a PhD in Nutritional Sciences and my expertise is in conducting and interpreting research related to my field. Please consult your physician before doing anything for prevention or treatment of COVID-19, and please seek the help of a physician immediately if you believe you may have COVID-19.

STAY SAFE AND HEALTHY!

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