Question: Could methylglyoxal be causing elevated fasting glucose in low-carbers?
Yes. I did my doctoral dissertation on methylglyoxal so I've covered it in a lot of different contexts, and the basic story is we know that diabetics have high methylglyoxal levels. We know that diabetics have high methylglyoxal-derived advanced glycation endproducts. And we know that this is true even when they're treated. Now that raises the question, does diabetes cause methylglyoxal to increase, or does methylglyoxal cause diabetes? And the answer is both.
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DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.