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Question: What does an upregulated GGT gene do to glutathione status?
Well, if you assume that whatever the genetic test told you is actually happening as increased GGT activity, then what it should do is break down blood glutathione and help the breakdown products get into the cell to increase intracellular glutathione. I think as to what it does to glutathione status measured in the blood, I don't know. Because on the one hand, it's probably going to break down glutathione in the blood. But in general, if you're improving glutathione status inside the cell in the liver, you're going to increase the export of glutathione.
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DISCLAIMER: I have a PhD in Nutritional Sciences and my expertise is in performing and evaluating nutritional research. I am not a medical doctor and nothing herein is medical advice.